Hans-Christian Åsheim
-
- Dean
- Faculty of Health Sciences and Technology
- Fakultet for helse og teknologi
Background
Hans-Christian Åsheim is Dean of the Faculty of Health and Technology at Kristiania University of Applied Sciences. He is a Professor of Immunology with a background in Molecular Biology.
Åsheim has previously served as a research group leader at The Norwegian Radium Hospital and Ullevål Hospital, and as Head of Department at Oslo and Akershus University College of Applied Sciences (now OsloMet) and at the University of Oslo.
Areas of expertise and research interests: Immunology, molecular biology, and ageing.
Employee details
Scientific Publications
- Prydz, Kristian, Simm, Roger, Davydova, Erna & Åsheim, Hans-Christian (2025). Ephrin-B1 regulates cell surface residency of heparan sulfate proteoglycans (HSPGs) and complexes with the HSPG CD44V3-10 and fibroblast growth factor receptors. Glycobiology. ISSN 0959-6658. 35(6) doi: 10.1093/glycob/cwaf020
- Sapkota, Dipak, Vallenari, Evan Michael, Tamatam, Dhanalakshmi, Schreurs, Olaf Joseph Franciscus, Pandey, Sushma, Søland, Tine Merete, Costea, Daniela Elena, Tokozlu, Burcu & aasheim, Hans-Christian (2022). Investigation of Cross-Reactivity of Anti-Ephrin-B2 Antibody
to Other Ephrin-B Members in an Immunohistochemical Study
in a Cohort of Oral Squamous Cell Carcinoma. Oral. ISSN 2673-6373. 2 doi: 10.3390/oral2020015
- Adusumalli, Ravi, Åsheim, Hans-Christian, Lupashin, Vladimir, blackburn, jessica b & Prydz, Kristian (2021). Proteoglycan synthesis in conserved oligomeric Golgi subunit deficient HEK293T cells is affected differently, depending on the lacking subunit. Traffic: The moving front of cell biology. ISSN 1398-9219. doi: 10.1111/tra.12804
- Rørvik, Gro Herredsvela, Liskiewicz, Krystyna Anna, Kryuchkov, Fedor, Naemi, Ali-Oddin, aasheim, Hans-Christian, Petersen, Fernanda Cristina, Küntziger, Thomas M. & Simm, Roger (2020). Cyclic di-adenosine monophosphate regulates metabolism and growth in the oral commensal streptococcus mitis. Microorganisms. ISSN 2076-2607. 8:1269(9) p 1-21. doi: 10.3390/microorganisms8091269
- Prydz, Kristian, Halstensen, Trond S., holen, Halvor Lauvstad & aasheim, Hans-Christian (2018). Ephrin-B3 binds both cell-associated and secreted proteoglycans. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 503(4) p 2212-2217. doi: 10.1016/j.bbrc.2018.06.140
- Aas, Vigdis, Sand, Kristin Larsen, Åsheim, Hans-Christian, Benestad, Haakon Breien & Iversen, Jens Gustav Heber (2013). C-Reactive Protein Triggers Calcium Signalling in Human Neutrophilic Granulocytes via FcγRIIa in an Allele-Specific Way. Scandinavian Journal of Immunology. ISSN 0300-9475. 77(6) p 442-451. doi: 10.1111/sji.12049
- Holen, Halvor Laustad, Zernichow, Lillian, Fjelland, Kristine Engelsen, Evenrød, Ida Marie, Prydz, Kristian, Tveit, Heidi & Åsheim, Hans-Christian (2011). Ephrin-B3 binds to a sulfated cell surface receptor. Biochemical Journal. ISSN 0264-6021. doi: 10.1042/BJ20100865
- Stavik, Benedicte, Skretting, Grethe, Åsheim, Hans-Christian, Tinholt, Mari, Zernichow, Lillian, Sletten, Marit, Sandset, Per Morten & Iversen, Nina (2011). Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility. BMC Cancer. ISSN 1471-2407. 11 doi: 10.1186/1471-2407-11-357
- Holen, Halvor, Zernichow, Lillian, Fjelland, Kristine, Evenrød, Ida Marie, Prydz, Kristian, Tveit, Heidi & Åsheim, Hans-Christian (2011). Ephrin-B3 binds to a sulfated cell-surface receptor. Biochemical Journal. ISSN 0264-6021. 433 p 215-223. doi: 10.1042/BJ20100865
- Warsame, Abdirashid Ali, Åsheim, Hans-Christian, Nustad, Kjell Johannes, Trøen, Gunhild, Tierens, Anne, Wang, Chia-Wei Vivian, Randen, Ulla, Dong, Phuc Hiep, Heim, Sverre, Brech, Andreas & Delabie, Jan (2011). Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity. Blood. ISSN 0006-4971. 118(12) p 3331-3339. doi: 10.1182/blood-2011-03-341651
- Holen, Halvor, Zernichow, Lillian, Fjelland, Kristine, Evenrød, Ida Marie, Tveit, Heidi & Åsheim, Hans-Christian (2011). Ephrin-B3 Binds Specifically to B Lymphocytes in Blood and Induces Migration. Scandinavian Journal of Immunology. ISSN 0300-9475. 74(2) p 144-154. doi: 10.1111/j.1365-3083.2011.02563.x
- Holen, Halvor, Nustad, Knut Gunnar & Åsheim, Hans Christian (2010). Activation of EphA receptors on CD4(+)CD45RO(+) memory cells stimulates migration. Journal of Leukocyte Biology. ISSN 0741-5400. 87(6) p 1059-1068. doi: 10.1189/jlb.0709497
- Holen, Halvor (2010). Eph receptor tyrosine kinases and ephrin ligands – expression, interaction and function in cancer and immunity. Unipub forlag. ISBN 9788282641210.
- Wälchli, Sebastian, Åsheim, Hans-Christian, Skånland, Sigrid Strand, Spilsberg, Bjørn, Torgersen, Maria Lyngaas, Rosendal, Ken Roger & Sandvig, Kirsten (2009). Characterization of clathrin and Syk interaction upon Shiga toxin binding. Cellular Signalling. ISSN 0898-6568. doi: 10.1016/j.cellsig.2009.03.005
- Hauge, Linda Helena, Fjelland, Kristine Engelsen, Sioud, Mouldy & Åsheim, Hans-Christian (2009). Evidence for the involvement of FAM110C protein in cell spreading and migration. Cellular Signalling. ISSN 0898-6568. doi: 10.1016/j.cellsig.2009.08.001
- holen, Halvor Lauvstad, Shadidi, Mohsen, Narvhus, Kristina, kjøsnes, oddveig, Tierens, Anne & Åsheim, Hans-Christian (2008). Signaling through ephrin-A ligand leads to activation of Src-family kinases, Akt phosphorylation, and inhibition of antigen receptor-induced apoptosis. Journal of Leukocyte Biology. ISSN 0741-5400. doi: 10.1189/jlb.1207829
- Wu, Weiwei, Slåstad, Heidi, Rosa-Carrillo, Daniel de la, frey, tom, Tjønnfjord, Geir, Boretti, Eva, Åsheim, Hans-Christian, horesji, vaclav & Lund-Johansen, Fridtjof (2008). Antibody array analysis with label-based detection and resolution of protein size. Molecular & Cellular Proteomics. ISSN 1535-9476. doi: 10.1074/mcp.M800171-MCP200
- Kolltveit, Kristin Melkevik, Granum, Stine, Åsheim, Hans-Christian, Forsbring, Monika, Sundvold-Gjerstad, Vibeke, Dai, Ke-Zheng, Molberg, Øyvind, Schjetne, Karoline Western, Bogen, Bjarne, shapiro, virginia, Johansen, Finn-Eirik, Schenck, Karl & Spurkland, Anne (2008). Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level. Molecular Immunology. ISSN 0161-5890. doi: 10.1016/j.molimm.2007.11.005
- Boye, Kjetil, Grotterød, Ida, Åsheim, Hans-Christian, Hovig, Eivind & Mælandsmo, Gunhild Mari (2008). Activation of NF-kappaB by extracellular S100A4: analysis of signal transduction mechanisms and identification of target genes. International Journal of Cancer. ISSN 0020-7136. doi: 10.1002/ijc.23617
- Hauge, Linda Helena (2008). Gene expression analysis in DLBCL; Identification and characterization of novel protein. Unipub forlag. ISBN 9788280724625.
- Ertesvåg, Åse, Åsheim, Hans-Christian, Naderi, Soheil & Blomhoff, Heidi Kiil (2007). Vitamin A potentiates CpG-mediated memory B-cell proliferation and differentiation: involvement of early activation of p38MAPK. Blood. ISSN 0006-4971. doi: 10.1182/blood-2006-09-046748
- Hjorthaug, Hanne Sagsveen & Åsheim, Hans-Christian (2007). Ephrin-A1 stimulates migration of CD8+CCR7+ T lymphocytes. European Journal of Immunology. ISSN 0014-2980. doi: 10.1002/eji.200737111
- Hauge, Linda Helena, Patzke, Sebastian & Åsheim, Hans-Christian (2007). Characterization of the FAM110 gene family. Genomics. ISSN 0888-7543. doi: 10.1016/j.ygeno.2007.03.002
- Wu, QH, Lind, GE, aasheim, Hans-Christian, Micci, F, Silins, I, Trope, CG, Nesland, JM, Lothe, RA & Suo, ZH (2007). The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers. Epigenetics. ISSN 1559-2294. 2(4) p 237-243.
- Patzke, Sebastian, Stokke, Trond & Åsheim, Hans-Christian (2006). CSPP and CSPP-L associate with centrosomes and microtubules and differently affect microtubule organization. Journal of Cellular Physiology. ISSN 0021-9541. doi: 10.1002/jcp.20725
- Patzke, S., Hauge, Linda Helena, Sioud, Mouldy, Finne, Eivind Farmen, Sivertsen, Einar, Delabie, Jan, Stokke, Trond & Åsheim, Hans Christian (2005). Identification of a novel centrosome microtubule-associated coiled-coil protein involved in cell cycle progression and spindle organization. Oncogene. ISSN 0950-9232. 24 p 1159-1173. doi: 10.1038/sj.onc.1208267
- Åsheim, Hans-Christian, Delabie, Jan & Finne, Eivind Farmen (2005). Ephrin-A1 binding to CD4+ T lymphocytes stimulates migration and induces tyrosine phosphorylation of PYK2. Blood. ISSN 0006-4971. doi: 10.1182/blood-2004-08-2981
- Torlakovic, Emina, Malecka, Agnieszka Maria, Myklebust, June Helen, Tierens, Anne, Åsheim, Hans-Christian, Smeland, Erlend B., Kvaløy, Stein & Delabie, Jan (2005). PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including BCL-6, CD10, CD20 and CD22: identification of PU.1 putative binding sites in the BCL-6 promotor. Journal of Pathology. ISSN 0022-3417. doi: 10.1002/path.1777
- Åsheim, Hans Christian, Delabie, Jan, Finne, E. F. & Finne, Eivind Farmen (2004). Ephrin-A1 binding to CD4+ T lymphocytes stimulates migration and induces tyrosine phosphorylation of PYK2. Blood. ISSN 0006-4971. doi: 10.1182/bloos-2004-08-2981
- Hauge, Linda Helena, Patzke, S., Delabie, Jan & Åsheim, Hans Christian (2004). Characterisation of a novel immunoglobulin-like domain containing receptor, ILDR1. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 323(3) p 970-978.
- Finne, Eivind Farmen, Munthe, Else & Åsheim, Hans Christian (2004). A new ephrin-A1 isoform (ephrin-A1 isoform b)with altered receptor binding properties abrogates the cleavage of ephrin-A1 isoform a. Biochemical Journal. ISSN 0264-6021. 379 p 39-46.
- Munthe, Else, Finne, E. F. & Åsheim, Hans Christian (2004). Expression and functional effects of Eph receptor tyrosine A family members on Langerhans like dendritic cell. BMC Immunology. ISSN 1471-2172. 5 p 1-9.
- Bønsdorff, Tina Bjørnlund, Eggen, Andre, Gautier, M, Åsheim, Hans-Christian, Rønningen, Knut, Lingaas, Frode & Olsaker, Ingrid (2003). Identification and physical mapping of genes expressed in the corpus luteum in cattle. Animal Genetics. ISSN 0268-9146. doi: 10.1046/j.1365-2052.2003.01023.x
- Wabakken, Troels Karl, Rian, Edith, Kveine, Marit & Åsheim, Hans-Christian (2003). The human solute carrier SLC41A1 belongs to a novel eukaryotic subfamily with homology to prokaryotic MgtE Mg2+ transporters. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. doi: 10.1016/s0006-291x(03)01030-1
- Wabakken, Troels Karl, Hauge, Helena, Finne, Eivind Farmen, Wiedlocha, Antoni & aasheim, Hans-Christian (2002). Expression of human protein tyrosine phosphatase epsilon in leukocytes: a potential ERK pathway-regulating phosphatase. Scandinavian Journal of Immunology. ISSN 0300-9475. 56 p 195-203.
- Wabakken, Troels Karl, Hauge, Helena, Funderud, Steinar & aasheim, Hans-Christian (2002). Characterization, expression and functional aspects of a novel protein tyrosine phosphatase epsilon isoform. Scandinavian Journal of Immunology. ISSN 0300-9475. 56 p 276-285.
- Ree, Anne Hansen, Bratland, Åse, Kroes, Roger A., Åsheim, Hans-Christian, Flørenes, Vivi Ann, Moskal, Joseph R., Fodstad, Øystein, Bruland, Øyvind & Mælandsmo, Gunhild Mari (2002). Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases. Anticancer Research. ISSN 0250-7005.
- Wang, Junbai, Delabie, Jan, aasheim, Hans-Christian, Smeland, Erlend B & Myklebost, Ola (2002). Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study. BMC Bioinformatics. ISSN 1471-2105.
- Patzke, Sebastian, lindeskog, mats, Munthe, Else & Åsheim, Hans-Christian (2002). Characterization of a novel human endogenous retrovirus, HERV-H/F, expressed in human leukemia cell lines. Virology. ISSN 0042-6822. doi: 10.1006/viro.2002.1615
- Wabakken, Troels Karl, Hauge, Linda Helena, Finne, Eivind Farmen, Wiedlocha, Antoni & Åsheim, Hans-Christian (2002). Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase. Scandinavian Journal of Immunology. ISSN 0300-9475. doi: 10.1046/j.1365-3083.2002.01126.x
- Munthe, Else & Åsheim, Hans-Christian (2002). Characterization of the human ephrin-A4 promoter. Biochemical Journal. ISSN 0264-6021. doi: 10.1042/BJ20011693
- Wang, Junbai, Delabie, Jan, Åsheim, Hans-Christian, Smeland, Erlend B. & Myklebost, Ola (2002). Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study. BMC Bioinformatics. ISSN 1471-2105. doi: 10.1186/1471-2105-3-36
- Rian, Edith, Wabakken, Troels Karl, Hauge, Linda Helena & Åsheim, Hans-Christian (2001). A Signal Sequence Trap based on Cell Enrichment using Anti-CD19 Antibody Coated Magnetic Beads. Scandinavian Journal of Immunology. ISSN 0300-9475. doi: 10.1046/j.1365-3083.2001.00925.x
- Åsheim, Hans-Christian, Munthe, Else, Funderud, Steinar, Smeland, Erlend B., Beiske, Klaus & Logtenberg, Ton (2000). A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes. Blood. ISSN 0006-4971.
- Fosså, Alexander, Siebert, R., Åsheim, Hans-Christian, Mælandsmo, Gunhild Mari, Berner, Aasmund, Fosså, Sophie Dorothea, Paus, Elisabeth, Smeland, Erlend B. & Gaudernack, Gustav (2000). Identification of nucleolar protein No55 as a tumour-associated autoantigen in patients with prostate cancer. British Journal of Cancer. ISSN 0007-0920. doi: 10.1054/bjoc.2000.1365
- Røsok, Øystein, Pedeutour, Florence, Odeberg, Jacob, Lundeberg, Joakim & Åsheim, Hans-Christian (2000). The C1orf9 gene encodes a putative transmembrane member of a novel protein family. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. doi: 10.1006/bbrc.1999.2016
- Munthe, Else, Rian, Edith, Holien, Toril, Rasmussen, Anne Marie, Levy, Finn Olav & Åsheim, Hans-Christian (2000). Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6. FEBS Letters. ISSN 0014-5793. doi: 10.1016/s0014-5793(99)01793-7
- Røsok, Øystein, Pedeutour, Florence, Ree, Anne Hansen & Åsheim, Hans-Christian (1999). Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis. Genomics. ISSN 0888-7543. doi: 10.1006/geno.1999.5922
- Odeberg, Jacob, Røsok, Øystein, Gudmundsson, Gudmundur, Ahmadian, Afshin, Roshani, Leyla, Williams, Cecilia, Uhlén, Mathias, Pontén, Fredrik, Åsheim, Hans-Christian & Lundeberg, Joakim (1998). Cloning and characterization of ZNF189, a novel human Krüppel-like zinc finger gene localized to chromosome 9q22-q31. Genomics. ISSN 0888-7543. doi: 10.1006/geno.1998.5309
- Spurkland, Anne, Brinchmann, Jan E., Markussen, Gunnar, Pedeutour, Florence, Munthe, Else, Lea, Tor, Lea, Tor, Vartdal, Frode & Åsheim, Hans-Christian (1998). Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites. Journal of Biological Chemistry. ISSN 0021-9258. doi: 10.1074/jbc.273.8.4539
- Åsheim, Hans-Christian, Pedeutour, Florence & Logtenberg, Ton (1998). Cloning, chromosal mapping, and tissue expression of the gene encoding the human Eph-family kinase ligand ephrin-A2. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. doi: 10.1006/bbrc.1998.9618
- Åsheim, Hans-Christian & logtenberg, ton (1997). Regulated expression of the Eph-related receptor tyrosine kinase Hek11 in early human B lymphopoiesis. Blood. ISSN 0006-4971.
- Åsheim, Hans-Christian, Pedeutour, Florence & Smeland, Erlend B. (1997). Characterization, expression and chromosomal localization of a human gene homologous to the mouse Lsc oncogene , with strongest expression in hematopoetic tissues. Oncogene. ISSN 0950-9232. doi: 10.1038/sj.onc.1200994
- Åsheim, Hans-Christian, Logtenberg, Ton & Larsen, Frank (1997). Subtractive hybridization for the isolation of differentially expressed genes using magnetic beads. Methods in molecular biology. ISSN 1064-3745. doi: 10.1385/115
- Åsheim, Hans-Christian, Aas-Eng, Anne, Deggerdal, Arne Helge, Smeland, Erlend B. & Funderud, Steinar (1995). Characterization of a promoter region supporting the transcription of human b-galactoside a2,6-sialyltransferase in HepG2 cells. Biochimica et Biophysica Acta. ISSN 0006-3002. doi: 10.1016/0167-4781(94)00250-7
- Bryne, Magne, Åsheim, Hans-Christian & Giercksky, Karl-Erik (1995). [Blocking of carbohydrate adhesion. A new principle for therapy of many conditions?]. M Bryne;H C Asheim;K E Giercksky. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001.
- aasheim, Hans-Christian, Deggerdal, Arne Helge, Smeland, Erlend B. & Hornes, Erik (1994). A simple subtraction method for the isolation of cell-specific genes using magnetic monodisperse polymer particles. BioTechniques. ISSN 0736-6205. 16(4) p 716-721. doi: 10.2144/btn-2019-0162
- Åsheim, Hans-Christian, Loukianova, Tanya, Deggerdal, Arne Helge & Smeland, Erlend B. (1994). Tissue specific expression and cDNA structure of a human transcript encoding a nucleic acid binding [oligo(dC)] protein related to the pre-mRNA binding protein K. Nucleic Acids Research (NAR). ISSN 0305-1048. doi: 10.1093/nar/22.6.959
- Åsheim, Hans-Christian, Aas-Eng, Anne, Deggerdal, Arne Helge, Funderud, Steinar, Blomhoff, Heidi Kiil & Smeland, Erlend B. (1993). Cell specific expression of human b -galactoside a 2,6-sialyltransferase transcripts differing in the 5' untranslated region. European Journal of Biochemistry (EJB). ISSN 0014-2956. doi: 10.1111/j.1432-1033.1993.tb17783.x
- Funderud, Steinar, Erikstein, Bjørn, Åsheim, Hans-Christian, Blomhoff, Heidi Kiil, Smeland, Erlend B. & Holte, Harald (1990). Functional properties of CD19+ B lymphocytes positively selected from buffy coats by immunomagnetic seperation. European Journal of Immunology. ISSN 0014-2980. doi: 10.1002/eji.1830200129
- Stamenkovic, Ivan, Åsheim, Hans-Christian, Deggerdal, Arne Helge, Blomhoff, Heidi Kiil, Smeland, Erlend B. & Funderud, Steinar (1990). The B cell antigen CD75 is a cell surface sialyltransferase. Journal of Experimental Medicine (JEM). ISSN 0022-1007. doi: 10.1084/jem.172.2.641
- Smeland, Erlend B., Holte, Harald, Funderud, Steinar, Blomhoff, Heidi Kiil, Torjesen, Peter A, aasheim, Hans-Christian & Stokke, Trond (1990). Inhibition of polyphosphoinositide breakdown and c-myc induction accompanying inhibition of human B-cell activation by two monoclonal antibodies against the leucocyte common antigen. Scandinavian Journal of Immunology. ISSN 0300-9475. 31(5) p 583-591. doi: 10.1111/j.1365-3083.1990.tb02809.x
Dissemination
- Meza, Trine Johansen & aasheim, Hans-Christian (2022). Fremtidens helseutdanning?
Vi må våge å sette spørsmålstegn ved om mer av den tradisjonelle behandlerrekrutteringen i helsesektoren holder mål 25–35 år frem i tid. Det haster. FULLTEKST
- Åsheim, Hans-Christian (2014). Der publisering gir økonomisk uttelling.
- Prydz, Kristian, Simm, Roger, Davydova, Erna & Åsheim, Hans-Christian (2025). Ephrin-B1 regulates cell surface residency of heparan sulfate proteoglycans (HSPGs) and complexes with the HSPG CD44V3-10 and fibroblast growth factor receptors. Glycobiology. ISSN 0959-6658. 35(6) doi:
